Full list of all 46 The Callisto Protocol achievements worth 1,540 gamerscore. It takes around 15-20 hours to unlock all of the achievements in the base game.
The base game contains 26 achievements worth 1,000 Gamerscore, and there are 5 DLC packs containing 20 achievements worth 540 Gamerscore.
Beat the game on any difficulty
Fully Upgrade One Weapon
Beat the game on Maximum Security difficulty
Harvest and read all implant bios
Uncover the mystery of Kallipolis
Grab twenty-five enemies with the GRP
Take down a security robot
Take down the two-head
Kill an enemy via GRP and a melee combo
Print a weapon for the first time
Print a weapon upgrade
Stab five blind enemies in the back
Take a photo using photo mode
Perfect dodge five times
Use melee or ranged weapons to take both arms off a living enemy
Kill ten enemies with environmental hazards
Use GRP to kill an enemy by throwing them into an environmental hazard
Find the Outer Way boarding craft
Elias gives Jacob a shiv
Activate the SHU
Survive the pipeslide
Return to the crashed ship
Reach the Hangar flight deck
Restore power to the old facility
Find the source
Get thrown back into original cell
Finish New Game Plus Mode
Finish Game in Hardcore Mode
Finish Game in Hardcore Mode NG+
Purchase all weapons and upgrades
Finish Game in Contagion Mode
Finish Game in Contagion Mode Without Dying
Complete Wave 50
Spend 20,000 Credits
Dismember 100 limbs in Riot Mode
Kill a Two-Head with a Hazard
Survive five consecutive waves without spending any Credits
Use the Power-up 10 times
Complete Riot Mode for the first time
Finish Final Transmission
Find all 8 Protocol Data Drives
Solve any Security Lock System in less than 7 seconds
Locate the Escape Pod
Killed your first Biobot!
Obtain the Kinetic Hammer
Destroy all Hammer Crates on the Factory Floor